Haemophilia A in older patients

Haemophilia A is due to defective or low levels of factor 8 (F8). Before the 1950s there was no therapy and patients often died before 30 years old, but by the 1950s patients could be treated with plasma or whole blood and from the 1960s by cryoprecipitate.  Freeze dried F8 became available from 1960€“70s but carried with it the possibility of blood-bourne disease, a disaster for haemophiliacs some of whom are now entering older age. In the early 1980s outbreaks of AIDS were identified and not long after Hepatitis C (HCV) was discovered. By 1985 blood was screened for HIV