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Transient global amnesia is widely regarded as one of the most remarkable neurological conditions in terms of its history, symptoms and signs. It presents classically with a sudden onset of severe anterograde amnesia. We describe here the epidemiology, clinical features, and management of this poorly recognised condition.

Clinically the prevalence of signifcant lower urinary tract symptoms and/or poor flow rises from around 13% in the 5th decade of life to between 28€“43% by the 7th and 8th decades of life. Histologically, benign prostatic hypertrophy is seen on autopsy from the age of 30 years with 88% of those beyond 80 years old afected. The risk of urinary retention in the 8th decade of life is between 0.9€“3.4% per year for symptomatic men.

Chronic pain is a frequent health problem in the elderly and is not part of the normal ageing process. The prevalence levels range between 45% and 80% in line with an age-related increase in patient comorbidity.

The burden of musculoskeletal foot pathology in the general population is frequently trivialised but causes patients signifcant impairment. This article aims to give clinicians who don't specialise in the foot, a basic understanding of how to recognise and provide first line treatment for common musculoskeletal foot pathologies.

When it comes to comparing men with women around the context of healthcare; men generally speaking, fare significantly worse than their female counterparts.

AHA is a rare autoimmune bleeding disorder characterised by IgG antibodies to coagulation factor VIII. It is a disease of the elderly and often presents with life-threatening or widespread subcutaneous bleeding. Management should always be led by a specialist haemophilia unit. Although treatment confers a roughly two-fold improvement in recovery and overall mortality, the risk of death remains significant.

Assisted suicide is a topical issue. Autonomy plays a central role in arguments for and against assisted suicide. The Kantian and Millean views of autonomy greatly infuence our thinking of this area in assisted suicide. An understanding of autonomy in relation to assisted suicide would allow us to evaluate the opposing views of this ofen controversial issue.

Delirium is common in both general and hospital practice. It ofen goes unrecognised and can be poorly managed. Early diagnosis and skilled assessment of patients with delirium enables prompt management and improves prognosis. This article explores how to assess patients presenting with confusion.

Movement disorders are encountered in all areas of medical practice and are generally associated with disorders of the basal ganglia. Tey can be broadly classifed into conditions with increased or paucity of movement, the former comprising tics, dyskinesias, tremor or chorea and the latter akinetic rigid syndrome.

Motor neuron disease (MND) is a devastating disease with a signifcant morbidity and shortened life expectancy. The needs of patients with MND are complex and hence a range of health professionals may be involved in their care, including GPs, geriatricians, chest physicians and palliative care physicians. This article aims to educate the non-neurologist about the clinical features of the disease, current concepts about its pathogenesis, prognosis and treatment strategies.

With the National Osteoporosis Society (NOS) Osteoporosis and Bone Conference 2012 taking place this month at the Manchester Central Convention Complex, we review the latest news and advances in bone health.

Hyperhidrosis is a condition characterised by abnormally increased sweating, in excess of that required for regulation of body temperature.

In the debate over whether assisted suicide should be legalised or not, dignity is a key battleground area.

Autoimmune limbic encephalitis is a rare but reversible cause of confusion or dementia that ofen evades diagnosis, leading to long-term neurological sequelae. It is becoming increasingly recognised and certain clinical features can be used to raise suspicion of the disease.

Although three-quarters of patients wish to die at home, only a quarter actually do so. A more concerted effort in primary care can increase the chances of a terminally ill patient fulfilling this wish. Liaison between the primary healthcare team, patient, relatives and carers, outside agencies and secondary care is essential to the success of domiciliary palliative care. The common symptoms such as pain, nausea, vomiting, constipation and breathlessness can usually be managed with medication at home.