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Peripheral neuropathy is common in older people. Although the ageing process itself may play a part, there are multiple other causes.

It has been well studied that prostate cancer will affect almost all males if they live for a sufficient duration, which is an important consideration in line with the demographic changes occurring within the developed world.

Depression is a common mental health problem in older adults. Studies have shown a wide range of brain structural and functional abnormalities in older depressed patients.

The key to optimal management of ankylosing spondylitis (AS) is early diagnosis. Whilst the typical late features of severe disease are easy to recognise, the early symptoms may be more difficult.

The risk of developing ovarian cancer increases with age and the condition primarily affects post-menopausal women.

Skin cancer incidences continue to rise and the older patients are at particular risk. Correct diagnosis and early referral is important to allow for expert management and early effective treatment.

Affective disorders are psychiatric diseases with multiple aspects, including biological, behavioural, social, and psychological factors. This article highlights the clinical features and the treatment options in older people.

Epilepsy is more common in older people, but diagnosis can be delayed by atypical presentation and non-specific symptoms. Mood problems such as depression and anxiety are also common.

Older people have a higher risk of completed suicide than any other age group. Mental health disorders, especially depression, have been consistently shown to have associations with suicidality in the older patient.

The National Osteoporosis Society is the only UK wide charity dedicated to improving the diagnosis, prevention and treatment of osteoporosis. This article reviews some of its current work.

GPs in the UK will, on average, each have 50 men on their list between the ages of 60 and 80 years who have moderate or severe urinary symptoms related to benign prostatic hyperplasia. This article discusses the prevalence and assessment in general practice of this condition.

Dementia is a devastating illness that leads to a progressive decline in a person's cognition and functioning. Patients frequently experience a wide array of behavioural and psychological symptoms, including agitation and aggression. These symptoms can be extremely distressing to patients and those who care for them. Antipsychotic medications have been the mainstay of pharmacological treatment and are used to treat these in patients with dementia in both the community and in hospital. However, recent studies have shown an increased risk of morbidity and mortality with long-term use.

Prostate cancer is the second leading cause of cancer death in men in the western world. Castrate resistant prostate cancer (CRPC) occurs when hormone therapy fails to arrest the growth of prostate cancer; death due to prostate cancer is a result of CRPC. Chemotherapy is used in the treatment of CRPC and has shown improvement in quality of life and a modest survival benefit. In this review we discuss new biological treatments as well as the role of radiotherapy and radionuclides in the treatment of CRPC.

Alcohol use disorders are common in the elderly, and on the increase as the population ages. While life changes may trigger the unhealthy use of alcohol, ageing physiology, comorbidities and polypharmacy can increase vulnerability to its effects. Alcohol use disorders are currently underdiagnosed in older people, in whom the early signs may be masked by altered patterns of drinking and non-specific presentations.

National guidance insists on discussion with mentally competent adults prior to making "Do not attempt resuscitation" orders about them. It is also evident that discussions related to resuscitation do not cause distress to the majority of adults. However, evidence shows that such discussions are rare, and that the resistance often lies with clinicians. Here, we explore the pertinent issues revealed in relevant research.