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Multiple myeloma is a malignant disease characterised by a clonal population of plasma cells in the bone marrow. The disease occurs in the elderly and results in lytic bone lesions, blood cytopenias and the production of monoclonal…
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About 50% of patients with diabetes mellitus worldwide suffer from diabetic peripheral neuropathy (DPN). The most common form of DPN is a symmetrical, predominantly sensory, polyneuropathy with distal onset and slow proximal progression.…
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There is little doubt that medical therapy has transformed the treatment of benign prostatic hypertrophy (BPH). The medical treatment of BPH continues to be based on two main classes of drugs, alpha adrenergic blockers and 5-alpha reductase…
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Giant cell arteritis is the most common chronic granulomatous vasculitis, mainly involving large and medium-sized vessels, and it almost exclusively affects patients older than 50 years. The initial event that triggers the cascade of…
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Diabetes is a major healthcare challenge for both primary and secondary care, affecting approximately one in 10 people over 65 years of age. An estimated 25% of people with diabetes undergo surgical procedures, often as a result of…
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Transient Ischaemic Attacks (TIAs) are defined as temporary neurological deficits lasting less than 24 hours. In this review, we aim to delineate TIAs to ensure prompt diagnosis and management. We do this by presenting a case series with a…
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In 2000, the World Health Organization reported depression to be the leading cause of disability, as measured by years lived with disability, and the fourth leading contributor to the global burden of disease. In this article, we will…
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Cancer of the bladder is a commonly diagnosed malignancy that is frequently seen in the elderly population and accounts for significant morbidity and mortality. The annual statistics for the UK report that 10,000 cases are diagnosed and…
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A range of effective drug treatments are available for Parkinson's disease (PD). However, long-term treatment is associated with the development of motor complications in a proportion of patients. The traditional view has been that…
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The publication of the 2006 NICE guidelines for Parkinson's disease may seem to have taken much of the management of patients with Parkinson's disease out of the hands of the GP and put them solely in the care of hospital specialists.…
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